The Guide to Investigation of Mouse Pregnancy

Publisher Elsevier Science

Format

eBook

2nd Edition 1st Edition

Quantity

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Publisher

Elsevier Science

Volume

Copyright

2014

ISBN13

9780123947949

Release

Format

eBook

Grade Level

College Freshman - College Senior

DDC
TBD

Overview

The Guide to Investigation of Mouse Pregnancy is the first publication to cover the mouse placenta or the angiogenic tree the mother develops to support the placenta. This much-needed resource covers monitoring of the cardiovascular system, gestational programming of chronic adult disease, epigenetic regulation, gene imprinting, and stem cells. Offering detailed and integrated information on how drugs, biologics, stress, and manipulations impact pregnancy in the mouse model, this reference highlights techniques used to analyze mouse pregnancy. Joining the ranks of much referenced mouse resources, The Guide to Investigation of Mouse Pregnancy is the only manual providing needed content on pregnancy in animal models for translational medicine and research.
Front Cover.
Half Title Page.
Other Frontmatter.
Title Page.
Copyright Page.
Contents.
Biographies.
Preface.
Contributors.
1: Atlas.
2: The Cycling and Pregnant Mouse: Gross Anatomy.
3: Implant Site Dissections.
4: Microscopic Anatomy of the Pregnant Mouse Uterus Throughout Gestation.
5: Anatomy of the Mouse Placenta Throughout Gestation.
6: Whole-Mount Immunohistochemistry of Early Implantation Sites.
7: Magnetic Resonance Imaging of the Mouse Placenta.
8: Basic Biology.
9: Reproductive Tract Changes During the Mouse Estrous Cycle.
10: First Cell Fate Decisions in Early Development: Towards Establishment of the Trophoblast Lineage.
11: Tetraploid Complementation Assay.
12: Biology of the Ectoplacental Cone.
13: Decidualization and Endometrial Extracellular Matrix Remodeling.
14: Postimplantation Development of the Chorioallantoic Placenta.
15: Unique Features of Endometrial Dynamics during Pregnancy.
16: Pathology Analysis of the Placenta.
17: Changes in Structures and Relationships of Trophoblasts, Leukocytes, and Maternal Vessels in Implantation Sites to Midpregnancy.
18: The Uteroplacental, Fetoplacental, and Yolk Sac Circulations in the Mouse.
19: Physiological Exchange across Mouse Placenta.
20: Hypoxia-Associated Regulation within Implantation Sites.
21: Leukocyte Population Dynamics and Functions at the Maternal–Fetal Interface.
22: In Vivo Tracking of Mononuclear Cells in the Virgin Uterus and in Implantation Sites.
23: Microchimerism in Mouse Pregnancy.
24: Systems Biology Analyses of the Placenta.
25: Contribution of Placental Genomic Imprinting and Identification of Imprinted Genes.
26: Epigenetics of Placental Development and Function.
27: Genome-Wide Analysis of the Mouse Deciduoma.
28: Conditional Gene Deletion in the Placenta Using the Cre-loxP System.
29: Genetic Engineering of Mice to Investigate Uterine Function in Early Pregnancy.
30: Lentivirus-Mediated Transduction of Optical Reporter Genes in Blastocysts for Placental Studies.
31: Blood
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The Guide to Investigation of Mouse Pregnancy

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Table of Contents