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Introduction to Biological and Small Molecule Drug Research and Development

INTRO TO BIOLOGICAL & SMLL MOLECULE DRUG RESEARCH & DEV

Drugs & Pharmacology

Health, Medicine & Nursing

Gt Product Group

Binding Format

Marketing Imprint Name

B2B GT

CL Carton Count

Imprint Name

B2B & B2C

Introduction to Biological and Small Molecule Drug Research and Development provides, for the first time, an introduction to the science behind successful pharmaceutical research and development programs. The book explains basic principles, then compares and contrasts approaches to both biopharmaceuticals (proteins) and small molecule drugs, presenting an overview of the business and management issues of these approaches. The latter part of the book provides carefully selected real-life case studies illustrating how the theory presented in the first part of the book is actually put into practice. Studies include Herceptin/T-DM1, erythropoietin (Epogen/Eprex/NeoRecormon), anti-HIV protease inhibitor Darunavir, and more. Introduction to Biological and Small Molecule Drug Research and Development is intended for late-stage undergraduates or postgraduates studying chemistry (at the biology interface), biochemistry, medicine, pharmacy, medicine, or allied subjects. The book is also useful in a wide variety of science degree courses, in post-graduate taught material (Masters and PhD), and as basic background reading for scientists in the pharmaceutical industry.

POST SECONDARY FOUR YEAR

COLFR

COLJR

COLSO

COLSR

Duration

Duration Unit Of Measure

Transaction Type

Front Cover.
Half Title Page.
Title Page.
Copyright Page.
Contents.
Biographies.
Preface.
1: Introduction to Enzymes, Receptors and the Action of Small Molecule Drugs.
2: Protein Structure and Function.
3: The Small Molecule Drug Discovery Process &#x2013; from Target Selection to Candidate Selection.
4: Protein Therapeutics (Introduction to Biopharmaceuticals).
5: Similarities and Differences in the Discovery and use of Biopharmaceuticals and Small-Molecule Chemotherapeutics.
6: Therapies for Type 2 Diabetes: Modulating the Incretin Pathway using Small Molecule Peptidase Inhibitors or Peptide Mimetics.
7: The Structure and Business of Biopharmaceutical Companies Including the Management of Risks and Resources.
8: Discovery and Development of the Anticancer Agent Gefitinib, an Inhibitor of the Epidermal Growth Factor Receptor Tyrosine Kinase.
9: Targeting HER2 by Monoclonal Antibodies for Cancer Therapy.
10: Recombinant Human Erythropoietin and its Analogues.
11: Lysosomal Storage Disorders: Current Treatments and Future Directions.
12: Hormone Replacement Therapy.
13: Design of the Anti-HIV Protease Inhibitor Darunavir.
14: The Case of Anti-TNF Agents.
15: Discovery of the Cholesterol Absorption Inhibitor, Ezetimibe.
Index.
Colour Plate.

Introduction to Biological and Small Molecule Drug Research and Development.css-1p8rvzy{position:absolute;padding-left:8px;}

Introduction to Biological and Small Molecule Drug Research and Development