Catecholamine Research in the 21st Century

Publisher Elsevier Science

Format

eBook

2nd Edition 1st Edition

Quantity

Add New

Publisher

Elsevier Science

Volume

Copyright

2013

ISBN13

9780128000731

Release

Format

eBook

Grade Level

College Freshman - College Senior

DDC
TBD

Overview

Through the use of extended graphical abstracts and some traditional text-only abstracts this collection provides, a record of and roadmap to, the research presented at The Tenth International Catecholamine Symposium (XICS) held in September of 2012. Organized around ten general themes, each is introduced by a short overview identifying interesting research programs, results and potential areas of growth. The collection is a roadmap to key research and future opportunities for new catecholamine research programs and will be of interest to neuroscientists and clinical neurologists interested in understanding the current and future state of catecholamine research.
Front Cover.
Half Title Page.
Title Page.
Copyright Page.
Table of Contents.
Preface.
1: Catecholamine Biosynthesis and Storage.
2: Genetic Manipulation of Catecholamine Signaling in the Mouse.
3: AADC Deficiency: Occurring in Humans; Modeled in Rodents; Treated in Patients.
4: Tyrosine Hydrolylase and Dopamine Beta-Hydroxylase: Role of Common Genetic Variation in Adrenergic Responses to Stress and in Hypertension.
5: Pharmacokinetic and Pharmacodynamic Properties of Etamicastat, a New DBH Inhibitor: Comparison to Nepicastat.
6: Estradiol-Mediated Regulation of Gene Expression of Catecholamine Biosynthetic Enzymes: The Role of Membrane-Initiated Signaling with Erα.
7: Structural Basis for Regulation of Tyrosine Hydroxlyase by the Catecholamines.
8: Unique Regulation of TH Gene Expression in Midbrain Dopamine Neurons.
9: Intracellular Stability of Tyrosine Hydroxylase: Phosphorylation and Proteasomal Digestion of the Enzyme.
10: The Peripheral Interaction of Tyrosine Hydroxylase and 14-3-3γ with Negatively Charged Phospholipidic Membranes.
11: Dynamic Regulation of Tyrosine Hydroxylase Gene Expression by Key Fate-Determining Transcription Factors during Dopaminergic Neuronal Development in Vivo and in Vitro.
12: Analysis of Tyrosine Hydroxylase Isoforms and Phosphorylation in Parkinson's Disease.
13: Non-dopaminergic Neurons Partly Expressing Dopaminergic Phenotype: Functional Significance and Regulation.
14: Developing Brain as an Endocrine Organ: Catecholamines Secretion and Endocrine Action.
15: Brainstem DOPAergic System.
16: Imaging Norepinephrine Transporters in Humans; Translational Research with PET.
17: Imaging the Vesicular Monoamine Transporter (VMAT2) in Neurodegenerative Diseases.
18: GTP Cyclohydrolase Regulation: Implications for Brain Development and Function.
19: Neonatal Diagnosis of Menkes Disease by a Pattern of Plasma Catechols.
20: Catecholamine Metabolites Affected by the Copper-Dependent Enzyme Dopamine-Beta-Hydroxylase Pr
Read More Read Less

Catecholamine Research in the 21st Century

Product Details

Overview

Table of Contents