This title offers a modern approach on the pathology of substances of abuse, offering an evidence based ethos for understanding the neurology of addictions. Volume One focuses on tobacco, alcohol, cannabinoids, and opioids, with each section providing data on the general, molecular/cellular, and structural/functional neurological aspects of a given substance, along with a focus on the adverse consequences of addictions. The title is aimed at students and researchers of behavioral neuroscience, neurology, addiction science, psychology, and research psychiatry.