Advances in Clinical Chemistry, Volume 82, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. This updated volume includes chapters on Calcium and Bone Metabolism Indices, Cytokines and MicroRNA in Coronary Artery Disease, Biological and molecular characterization of circulating tumor cells: A creative strategy for precision medicine?, Towards a blood-borne biomarker of chronic hypoxemia: Red cell distribution width and respiratory disease, miRNAs: nanomachines that micromanage the pathophysiology of Diabetes mellitus, and Fortilin, a potential target for the prevention and treatment of human diseases.