Overview
Completely revised and updated, Human Herpesviruses HHV-6A, HHV-6B & HHV-7, Third Edition, delivers a thorough review of HHV-6, from foundational explorations of classification, molecular biology, and chromosomal integration of the virus to clinical details, including pathologic features of infection, and clinical effects on various organ systems. The work now includes coverage of HHV-7, a virus that remains underestimated in transplant reactivation, seizures, and encephalitis. The book examines the role of HHV-6 in myriad diseases, including cognitive disorders following bone marrow transplant, mesial temporal lobe epilepsy, multiple sclerosis, autoimmune disease, encephalitis, Hodgkin's disease lymphoma (HHV-6B), and glioma (HHV-6A). Descriptions of novel molecular and serological diagnostic assays, along with detailed protocols, are included to aid researchers and clinicians in discriminating potential false positives originating from chromosomally integrated HHV-6 and in differentiating between active and latent infection. Human Herpesviruses HHV-6A, HHV-6B & HHV-7, Third Edition is a valuable reference for epidemiologists, virologists, practicing clinicians, infectious disease specialists, pathologists, herpes virus researcher.
