Prescription opioid medication abuse has been declared a national crisis by experts in medicine, substance use, public health, and pain management, culminating in a declaration made by the President of the United States that opioid misuse and abuse is a national health emergency. In this comprehensive text, expert scholars analyze and address a wide range of issues in, obstacles to, and potential solutions for this emergency, which caused more than 50,000 deaths in 2016 alone. It covers a variety of topics related to prescription misuse from both clinical and academic perspectives. After an opening containing background material on the most commonly misused medications, chapters examine subgroups engaged in misuse and special medical environments where misuse issues are key. They then cover U.S. policy, perspectives outside the U.S., and theories that may explain the misuse phenomena. This book will serve as a resource for students and professionals in fields related to prescription drug abuse-including psychology, sociology, medicine, and public policy-and is accessible to individuals not trained in these fields.