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This book covers a broad area of engineering research in translational medicine. Leaders in academic institutions around the world contributed focused chapters on a broad array of topics such as: cell and tissue engineering (6 chapters), genetic and protein engineering (10 chapters), nanoengineering (10 chapters), biomedical instrumentation (4 chapters), and theranostics and other novel approaches (4 chapters). Each chapter is a stand-alone review that summarizes the state-of-the-art of the specific research area.Engineering in Translational Medicine gives readers a comprehensive and in-depth overview of a broad array of related research areas, making this an excellent reference book for scientists and students both new to engineering/translational medicine and currently working in this area.

Engineering in Translational Medicine

POST SECONDARY FOUR YEAR

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ENGINEERING IN TRANSLATIONAL MEDICINE

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Front Cover.
Half Title Page.
Title Page.
Copyright Page.
Preface.
Acknowledgments.
Contents.
Contributors.
1: Engineering in Translational Medicine: An Introduction.
2: Cell and Tissue Engineering.
3: Stem Cells: The Holy Grail of Regenerative Medicine.
4: Engineering T Cells to Target Tumor Cells.
5: Engineering Biomaterials for Anchorage-Dependent and Non-Anchorage-Dependent Therapeutic Cell Delivery in Translational Medicine.
6: Tissue Engineering Applications for Peripheral Nerve Repair.
7: Structure, Function, and Development of Blood Vessels: Lessons for Tissue Engineering.
8: Engineering Gene-Activated Matrices for the Repair of Articular Cartilage Defect.
9: Genetic and Protein Engineering.
10: Engineering Luciferases for Assays and Imaging.
11: Engineered Split Reporter Systems for Molecular Imaging of Protein&#x2013;Protein Interactions in Living Subjects.
12: Engineering Aspects of Bioluminescence Resonance Energy Transfer Systems.
13: Antibody Engineering in Translational Medicine.
14: Engineered Affibodies in Translational Medicine.
15: Alternative Protein Scaffolds for Molecular Imaging and Therapy.
16: Engineering Multivalent and Multispecific Protein Therapeutics.
17: Engineering Aptamers for Biomedical Applications: Part I.
18: Engineering Aptamers for Biomedical Applications: Part II.
19: Engineering DNA Vaccines for Cancer Therapy.
20: Nanoengineering.
21: Multifunctional Nanoscale Delivery Systems for Nucleic Acids.
22: Engineering Nanomaterials for Biosensors and Therapeutics.
23: Engineering Fluorescent Nanoparticles for Biomedical Applications.
24: Magnetic Nanoparticles for Biomedical Applications: From Diagnosis to Treatment to Regeneration.
25: Engineering Upconversion Nanoparticles for Biomedical Imaging and Therapy.
26: Engineering of Mesoporous Silica Nanoparticles for In Vivo Cancer Imaging and Therapy.
27: Engineering Carbon Nanomaterials for Stem Cell-Based Tissue Engineering.
28: Engineering Peptide-Based Carriers for Drug and Gene Delivery.
29: Activation Approaches on Delivery of Imaging and Therapeutic Agents.
30: Opportunities for New Photodynamic Molecular Beacon Designs.
31: Biomedical Instrumentation.
32: Engineering the Next-Generation PET Detectors.
33: Photoacoustic Imaging: Development of Imaging Systems and Molecular Agents.
34: Engineering Miniature Imaging Instruments.
35: Engineering Small Animal Conformal Radiotherapy Systems.
36: Theranostics and Other Novel Approaches.
37: Plasmonic Nanobubbles for Cancer Theranostics.
38: Cell-Based Microfluidic Assays in Translational Medicine.
39: Engineering of Photomanipulatable Hydrogels for Translational Medicine.
40: Engineering AApeptides for Translational Medicine.

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Engineering in Translational Medicine