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Structural and Functional Characterization of the Immunoproteasome

ST: STRUCTURAL & FUNCTNL CHRCTRZTN OF IMMUNOPROTEASOME

Chemistry

Mathematics & Science

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B2B GT

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B2B & B2C

In this acclaimed thesis, Eva Maria Huber reveals ground-breaking results by elucidating the crystal structure of the murine immunoproteasome in complex with a selective inhibitor. Huber does this by performing multidisciplinary methodologies including X-ray crystallography, fluorescence spectroscopy and mutagenesis experiments. Her exceptional results explore the immunoproteasome complex structures and are of outstanding importance for future scientific research especially in the pharmaceutical industry. These results will enable the functional analysis of individual proteasome subunits and support the development of novel drugs for autoimmune diseases such as multiple sclerosis or rheumatoid arthritis.

POST SECONDARY FOUR YEAR

COLFR

COLJR

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COLSR

Duration

Duration Unit Of Measure

Transaction Type

Front Cover.
Half Title Page.
Other Frontmatter.
Title Page.
Copyright Page.
Other Frontmatter.
Dedication.
Supervisor&#x0027;s Foreword.
Acknowledgments.
Contents.
Abbreviations.
Introduction.
1: Objective.
2: Materials and Methods.
3: Results.
4: Discussion.
Appendix.

Structural and Functional Characterization of the Immunoproteasome.css-1p8rvzy{position:absolute;padding-left:8px;}

Structural and Functional Characterization of the Immunoproteasome